Dagne Dover Landon Neoprene Carryall Bag - Large

Roomy enough to fit a weekend's worth of clothes, yet compact enough to fit under an airport seat, this bag has one of the best designs we've tried.
Pros and Cons
Pros
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Repels stains
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Plenty of internal pockets
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Smart external design for savvy travelers
Cons
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Can crease if not stored properly